V. Petrovic, J.R. Blasco, L. Portolés, I. Morales, V. Primo, C. Atienza, J.F. Moreno, V. Belloch:

A study of mechanical and biological behavior of porous Ti6Al4V fabricated on EBM;

Taylor & Francis Group, London, 2012



A.Palmquist, A.Snisb, L.Emanuelssona, M.Brownec, P.Thomsena;

Electron beam melted Free Form Fabricated titanium alloy implants: A 6 months in vivo study in Sheep;

9th World Biomaterials Congress



Ciupik Lechoslaw, Kierzkowska Agnieszka, Jacek Cecek, Czercy Pieniazek, Jacek Sterna, Monika Cieslik-Gorna: The use of incremental technology to produce 3D Truss Ti6Al4V implants which improve the spinal treatment effectiveness. Key Engineering Materials, ISSN:1662-9795 Vol. 687 pp 179-184


A. Hölzl, F. Suleymanov, P. Strube:

1-year results for a titanium mesh Cage with as new surface design for TLIF. DWG Abstract 10. Jahrestagung 2016, Hannover



Peter Thomsen,1 Johan Malmstrom,1 Lena Emanuelsson,1 Magnus Rene ́ ,2 Anders Snis:

Electron Beam-Melted, Free-Form-Fabricated Titanium Alloy Implants: Material Surface Characterization and Early Bone Response in Rabbits

J Biomed Mater Res B Appl Biomater. 2009 Jul;90(1):35-44. doi: 10.1002/jbm.b.31250.



B.M. Hölper, V. Göktas, M. Eichler:

Evaluation of a frame/porous structered "Carving" interbody fusion Cage in 34 patients with lumbar 360° MIS Spondylodesis

The Journal of Spine Surgery 1 (5) 2013



Nemoto O1, Asazuma T, Yato Y, Imabayashi H, Yasuoka H, Fujikawa A.:

Comparison of fusion rates following transforaminal lumbar interbody fusion using polyetheretherketone cages or titanium cages with transpedicular instrumentation.

Eur Spine J. 2014 Oct;23(10):2150-5. doi: 10.1007/s00586-014-3466-9. Epub 2014 Jul 12.



Rene Bolivars-Navarrete, DDS, PhDa,  Rolando A. Gittens, MSb,  Jennifer M. Schneider, MSc,  Sharon L. Hyzy, BSa,d,  David A. Haithcock, BSa,  Peter F. Ullrich, MDe,  Zvi Schwartz, DMD, PhDa,f, and  Barbara D. Boyan, PhDa,*

Osteoblasts exhibit a more differentiated phenotype and increased bone morphogenetic protein production on titanium alloy substrates than on poly-ether-ether-ketone

Spine J . 2012 March ; 12(3): 265–272. doi:10.1016/j.spinee.2012.02.002



Lincks J, Boyan BD, Blanchard CR, Lohmann CH, Liu Y, Cochran DL, et al.

Response of MG63 Osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition.

Biomaterials. 1998; 19(23):2219–32.9884063. [PubMed: 9884063]


Schwartz Z, Raz P, Zhao G, Barak Y, Tauber M, Yao H, et al.

Effect of micrometer-scale roughness of the surface of Ti6Al4V pedicle screws in vitro and in vivo. J Bone Joint Surg Am. 2008; 90(11):2485–98.18978418. [PubMed: 18978418]



Rene Olivares-Navarrete, DDS, PhD,  Sharon L. Hyzy, BS,  Rolando A. Gittens I., MS, Jennifer M. Schneider, MS,  David Haithcock, BS,  Peter Ullrich, MD,  Paul J. Slosar, MD, Zvi Schwartz, DMD, PhD and  Barbara D. Boyan, PhD

Rough Titanium Alloys Regulate Osteoblast Production of Angiogenic Factors

 Spine J. 2013 November ; 13(11): . doi:10.1016/j.spinee.2013.03.047.



Rene Olivares-Navarrete , DDS, PhD , * Sharon L. Hyzy , MS , * Paul J. Slosar , MD , † Jennifer M. Schneider , MS , ‡ Zvi Schwartz , DMD, PhD , * § and Barbara D. Boyan , PhD *: Implant Materials Generate Different Peri-implant Inflammatory Factors

SPINE Volume 40 (2015) , Number 6 , pp 399 - 404